
Cataloguenumber
ANT-689
Synonyms
ACAD3,SCAD,EC1.3.99.2,Short-chainspecificacyl-CoAdehydrogenase,mitochondrial,Butyryl-CoAdehydrogenase,ACADS.
Type
Introduction
ACADSisatetramericmitochondrialflavoprotein,whichispartoftheacyl-CoAdehydrogenasefamily.ACADScatalyzesthefirststepofthemitochondrialfattyacidbeta-oxidationpathway.MutationsinACADShavebeenassociatedwithShortChainAcyl-CoADehydrogenaseDeficiency.
Clone
PAT8B10AT.
PhysicalAppearance
Immunogen
Anti-humanACADSmAb,isderivedfromhybridizationofmouseF0myelomacellswithspleencellsfromBALB/cmiceimmunizedwithrecombinanthumanACADSaminoacids25-412purifiedfromE.coli.
IgSubclass
MouseIgG2a heavychainandklightchain.
PurificationMethod
ACADSantibodywaspurifiedfrommouseasciticfluidsbyprotein-Aaffinitychromatography.
Formulation
1mg/mlcontainingPBS,pH-7.4,10%Glyceroland0.02%SodiumAzide.
StorageProcedures
StABIlity/ShelfLife
Applications
ACADSantibodyhasbeentestedbyELISA,Westernblotanalysis,FlowcytometryandICC/IFtoassurespecificityandreactivity.Sinceapplicationvaries,however,eachinvestigationshouldbetitratedbythereagenttoobtainoptimalresults.