
Cataloguenumber
PRO-238
Synonyms
Thioredoxin-likeprotein4B,Dim1-likeprotein,TXNL4B,DIM2,DLP.
Introduction
TXNL4BisamemberoftheDIM1familywhichhasavitalroleinpro-mRNAsplicing.TXNL4BisrequiredincellcycleprogressionforS/G2transitionandinteractswithPRPF6subunitofthespliceosome.
Description
TXNL4BproducedinE.Coliisasingle,non-glycosylatedpolypeptidechaincontaining185aminoacids(1-149a.a)andhavingamolecularmassof21.1kDa.
TXNL4Bisfusedtoa36aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
TXNL4Bproteinsolution(0.5mg/ml)containing20mMTris-HClbuffer(pH8.0),1mMDTT,30%glyceroland100mMNaCl.
StABIlity
TXNL4BHumanRecombinantalthoughstableat4°Cfor1week,shouldbestoredbelow-18°C.
Pleasepreventfreezethawcycles.
Purity
Aminoacidsequence
MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSMSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYLVDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIYRGAMRGKLIVQSPIDPKNIPKYDLLYQDI.