Prospec/U2AF1 Human/PRO-1461/1mg
商品编号：
PRO-1461
品牌：
prospecbio
市场价：
¥54000.00
美元价：
22950.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Catalogue number
PRO-1461
Synonyms
Splicing factor U2AF 35 kDa subunit, U2 auxiliary factor
35 kDa subunit, U2 small nuclear RNA auxiliary factor 1, U2 snRNP auxiliary
factor small subunit, U2AF35, U2AFBP, FP793, RNU2AF1, RN.
Introduction
U2AF1
is a member of the splicing factor SR family. U2 auxiliary factor, comprising a
large and a small
subunit, is a non-snRNP protein essential for the binding of U2 snRNP to the
pre-mRNA branch site.U2AF1 is the small subunit which plays a vital role in
both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between
the large subunit and proteins bound to the enhancers. U2 small nuclear RNA
auxiliary factor 1 (U2AF1) is a protein-coding gene. Among the diseases which
are associated with U2AF1:Myoclonus Epilepsy and progressive Myoclonus Epilepsy.
Description
U2AF1 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 263 amino acids (1-240 a.a) and having
a molecular mass of 30.3kDa.
U2AF1 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
U2AF1 protein solution (1mg/ml) containing 20mM Tris-HCl
buffer (pH 8.0), 0.4M UREA and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMAEYLAS IFGTEKDKVN CSFYFKIGAC RHGDRCSRLH NKPTFSQTIL
IQNIYRNPQN SAQTADGSHC AVSDVEMQEH YDEFFEEVFT EMEEKYGEVE EMNVCDNLGD HLVGNVYVKF
RREEDAEKAV IDLNNRWFNG QPIHAELSPV TDFREACCRQ YEMGECTRGG FCNFMHLKPI SRELRRELYG RRRKKHRSRS RSRERRSRSR
DRGRGGGGGG GGGGGGRERD RRRSRDRERS GRF
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作，1947年出生于以色列。1991-1997创建ReProGen 公司，从事细胞因子和趋化因子的大量生产及纯化；1997-2000创建ProSpec-TechnoGene，主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。
ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.
Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....
Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.
ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.
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