
Cataloguenumber
PRO-1266
Synonyms
Introduction
ERLipidRaftAssociated2(ERLIN2)isadomain-containingproteinwhichisamemberoftheband7/mec-2family.ERLIN2isaubiquitouslyexpressed339aminoacidprotein.ERLIN2whichislocalizedtothelipidraft-likedomainsinthemembraneoftheendoplasmicreticulum(ER),playsakeyroleintheER-associateddegradation(ERAD)pathwaythateliminatesmetabolicallyregulatedandabnormalproteinsfromtheER.
Description
Source
PhysicalAppearance
Formulation
ERLIN2proteinsolution(1mg/ml)containing20mMTris-HClbuffer(pH8.0),2MUreaand20%glycerol.
StABIlity
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.
Purity
Aminoacidsequence
MGSSHHHHHHSSGLVPRGSHMGSKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYKSVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKIHHELNQFCSVHTLQEVYIELFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAIRRNYELMESEKTKLLIAAQKQKVVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEKKISEIEDAAFLAREKAKADAECYTAMKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKDIPNMFMDSAGSVSKQFEGLADKLSFGLEDEPLETATKEN.