
Cataloguenumber
PRO-902
Synonyms
Myosinregulatorylightchain12A,MLC-2B,MyosinRLC,Myosinregulatorylightchain2nonsarcomeric,MyosinregulatorylightchainMRLC3,MYL12A,MLCB,MRLC3,RLC,MRCL3,MYL2B.
Introduction
Myosinregulatorylightchain12A(MYL12A)hasavitalroleinregulationofbothsmoothmuscleandnonmusclecellcontractileactivityviaitsphosphorylation.TheMYL12Aproteinisinvolvedincytokinesis,receptorcapping,andcelllocomotion.
Description
MYL12AHumanRecombinantproducedinE.Coliisasingle,non-glycosylatedpolypeptidechaincontaining195aminoacids(1-171a.a.)andhavingamolecularmassof22.4kDa.
MYL12Aisfusedtoa24aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
StABIlity
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.
Purity
Aminoacidsequence
MGSSHHHHHHSSGLVPRGSHMGSHMSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD.