
Cataloguenumber
PRO-2440
Synonyms
NKG2-A/NKG2-BtypeIIintegralmembraneproteinisoformNKG2-A,KLRC1,KillerCellLectin-LikeReceptorSubfamilyC,Member1,KLRC1,CD159A,NKG2,NKG2A,CD159antigen-likefamilymemberA,NKcellreceptorA,NKG2-A/B-activatingNKreceptor.
Introduction
KillerCellLectin-LikeReceptorSubfamilyC,Member1(KLRC1)isapartofthekillercelllectin-likereceptorfamily.KLRC1functionsasareceptorforthedetectionofMHCclassIHLA-EmoleculesbyNKcellsandsomecytotoxicT-cells.KLRC1isalsoconnectswithCD94andisexpressedonNKcellsandsomeactivatedTcell.
Description
KLRC1HumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining149aminoacids(94-233a.a.)andhavingamolecularmassof17.1kDa(MolecularsizeonSDS-PAGEwillappearatapproximately18-28kDa).KLRC1isexpressedwitha9aminoacidsHistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
KLRC1proteinsolution(0.25mg/ml)containsPhosphateBufferedSaline(pH7.4)and10%glycerol.
StABIlity
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADPPSTLIQRHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKLHHHHHH.