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当前位置: 首页 > 产品中心 > cytokine > Prospec/FNDC5 Human, Yeast/PRO-1663/10µg
商品详细Prospec/FNDC5 Human, Yeast/PRO-1663/10µg
Prospec/FNDC5 Human, Yeast/PRO-1663/10µg
Prospec/FNDC5 Human, Yeast/PRO-1663/10µg
商品编号: PRO-1663
品牌: prospecbio
市场价: ¥2600.00
美元价: 1170.00
产地: 美国(厂家直采)
公司:
产品分类: 细胞因子
公司分类: cytokine
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Cataloguenumber

PRO-1663

Synonyms

FibronectintypeIIIdomain-containingprotein5,FibronectintypeIIIrepeat-containingprotein2,Irisin,FRCP2,FNDC5.

Introduction

FibronectinTypeIIIDomainContaining5(Irisin)isanewlydiscoveredhormone,secretedintocirculationbymuscle,whichactsonwhiteADIpocytesandpromotesWAT“browning”.r-Irisincanreducebodyweightandcauseinductionofbrownadipocyteinvivo,includingacapacityforThermogenicenergyexpendituremediatedbyuncouplingprotein1(UCP-1).Irisinmatureproteiniscomprisedof110aminoacidresiduesandtwopotentialglycosylationsites.HighlevelsofIrisincanbefoundintheheartwhereasVerylowexpressionisfoundinthecolon,pancreasandspleen,ifany.

Description

FibronectinTypeIIIDomainContaining5HumanRecombinantproducedinyeastisaglycosylated,polypeptidechaincontaining110aminoacidsandhavingamolecularmassof20-25kDa.
FNDC5ispurifiedbyproprietarychromatographictechniques.

Source

 Yeast.

PhysicalAppearance

SterileFilteredWhitelyophilized(freeze-dried)powder.

Formulation

TheFNDC5waslyophilizedfrom0.45µmfilteredsolutioninPBS.

Solubility

ItisrecommendedtoreconstitutethelyophilizedFibronectinTypeIIIDomainContaining5insterile18M-cmH2Onotlessthan100µg/ml,whichcanthenbefurtherdilutedtootheraqueoussolutions.

StABIlity

LyophilizedFibronectinTypeIIIDomainContaining5althoughstableatroomtemperaturefor3weeks,shouldbestoreddesiccatedbelow-18°C.UponreconstitutionFNDC5shouldbestoredat4°Cbetween2-7daysandforfutureusebelow-18°C.
Pleasepreventfreeze-thawcycles.

Purity

Greaterthan98.0%asdeterminedbySDS-PAGE.

Aminoacidsequence

S_P__S__A__P__V__N__V__T__V__R__H__L__K__A__N__S__A__V__V__S_

W__D__V__L__E__D__E__V__V__I__G__F__A__I__S__Q__Q__K__K__D_V__R__M__L__R__F__I__Q__E__V__N__T__T__T__R__S__C__A__L__W_

_D__L__E__E__D__T__E__Y__I__V__H__V__Q__A__I__S__I__Q__G__Q_

S__P__A__S__E__P__V__L__F__K__T__P__R__E__A__E__K__M__A__S_K

__N__K__D__E__V__T__M__K__E.

BIOLOGicalActivity

ThebiologicalactivityofrecombinanthumanirisinwasmeasuredbytheabilitytoinduceUCP-1expressionofadipocytes.Thespecificactivityis10ng/ml.

Usage

Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theymaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.
品牌介绍
    ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作,1947年出生于以色列。1991-1997创建ReProGen 公司,从事细胞因子和趋化因子的大量生产及纯化;1997-2000创建ProSpec-TechnoGene,主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。       ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.       Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....       Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.       ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.