Cataloguenumber
PRO-211
Synonyms
Calcium-bindingprotein7,CaBP7,CalneuronII,Calneuron-2,CABP7,CALN2.
Introduction
Calcium-bindingprotein7(CABP7)contains2EF-handdomains.CABP7negativelyregulatesGolgi-to-plasmamembranetraffickingbyinteractingwithPI4KBandinhibitingitsactivity.TheCaBPfamilyofEF-handcontainingsmallCa(2+)-bindingproteinshaslatelyemergedassignificantregulatorsofmultipletargetsessentialtonormalneuronalfunctioninthemammaliancentralnervoussystem.
Description
CABP7producedinE.Coliisasingle,non-glycosylatedpolypeptidechaincontaining208aminoacids(1-188a.a.)andhavingamolecularmassof23.7kDa.
CABP7isfusedtoa20aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
StABIlity
CABP7HumanRecombinantalthoughstableat4°Cfor1week,shouldbestoredbelow-18°C.
Pleasepreventfreezethawcycles.
Purity
Aminoacidsequence
MGSSHHHHHHSSGLVPRGSHMPFHPVTAALMYRGIYTVPNLLSEQRPVDIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDFEEFVTLLGPKLSTSGIPEKFHGTDFDTVFWKCDMQKLTVDELKRLLYDTFCEHLSMKDIENIIMTEEESHLGTAEECPVDVETCSNQQIRQTCVRKS.