Cataloguenumber
ENZ-137
Synonyms
ADP-ribosepyrophosphatasemitochondrial,ADP-ribosediphosphatase,ADP-ribosephosphohydrolase,Adenosinediphosphoribosepyrophosphatase,ADPR-PPase,Nucleosidediphosphate-linkedmoietyXmotif9,Nudixmotif9,NUDT9,NUDT10,PSEC0099,UNQ3012/PRO9771.
Introduction
NUDT9isamemberofasuperfamilyofNudixhydrolases.NUDT9functionsasahighlyspecificadenosinediphosphateribosepyrophosphatasewhichhydrolyzesADPribosetoAMPandribose5"-phosphate.Inaddition,NUDT9maybeinvolvedintheregulationofthemenstrualcycleandmayberelatedtotheproliferationofglandularcellsinthehumanendometrium.
Description
NUDT9producedinE.Coliisasingle,non-glycosylatedpolypeptidechaincontaining325aminoacids(47-350a.a.)andhavingamolecularmassof36.5kDa(molecularweightonSDS-PAGEwillappearhigher).
NUDT9isfusedtoa21aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
NUDT9proteinsolution(1mg/ml)containing20mMTris-HClbuffer(pH8.0),10%glycerol,1mMDTTand0.1MNaCl.
StABIlity
NUDT9HumanRecombinantalthoughstableat4°Cfor1week,shouldbestoredbelow-18°C.
Pleasepreventfreezethawcycles.

