
Cataloguenumber
HOR-272
Introduction
PMSGHormoneisawellknowusedhormonetogetherwith progestogen toincreaseovulation justbeforeto artificialinsemination.PMSGhormoneisaplacentalglycoproteinproducedfromtheserumofpregnantmares.PMSGcomprisesofanalfasubunitandabetasubunit.PMSGhormoneissecretedfromendometrialcupswithinthepregnantmareuterusagingfrom40to130daysintotheir maturation,andonceextracted,itcanbeenusedtopromoteartificially estrus infemale animals.TheseassembliesproducePMSGhormonetoinducemare"sovarianandrepsouctivestructures.PMSGcaninducethegrowthoffolliclesbyovariesandresultsinovulatation.PMSGhormonehasanabouta4dayhalf-lifeofbioactivityinspeciesotherthanhorses.TheextendedBIOLOGicalactivitycancauseovarianstimulationandovulation.However,PMSGusealoneoftencausescysticovariandiseasebecauseoftheunrestrainedovarianstimulationandduetothesugarmoleculeswhichdecreaseclearanceofthehormone.PMSGismorelikelytobeusedthanotherpituitaryhormonesduetotheextendedcirculatory half-life.PMSGsolelyexhibitsluteinizinghormonelikeactivity,howeverinotheranimalclassesithasFSH&LHlikeactivity.
Description
PMSGisacomplexglycoproteinobtainedfromtheserumofpregnantmares.This43-63kdaproteiniscapableofsupplementingandbeingsubstitutedforthefolliclestimulatingandinterstitialcell-stimulatinghormoneoftheanteriorpituitaryglandinboththemaleandfemale.ThusPMSG-Intervetstimulatesdevelopmentoftheovarianfollicleinthefemale.
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PhysicalAppearance
Formulation
Solubility
StABIlity
Usage
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.
References
1.Title:REPRODUCTIVECYCLICITYANDPROFILESINPOSTPARTUMRAMBOUILLETEWESTREATEDCONTAININGINTRAVAGINALINSERTANDPMSG.
Publication:Proceedings,WesternSection,AmericanSocietyofAnimalScienceVol.62,2011
Link:http://www.asas.org/docs/western-section/2011-western-section-proceedings.pdf?sfvrsn=47455f63_0
2.Title:CorrelationoftheMitochondrialActivityofTwo-CellEmbryosProducedInVitroandtheTwo-CellBlockInKunmingandB6C3F1Mice
Link: http://onlinelibrary.wiley.com/doi/10.1002/ar.20890/full