Cataloguenumber
PRO-2409
Synonyms
CD84Molecule,SignalingLymphocyticActivationMolecule5,LeukocyteDifferentiationAntigenCD84,CD84Antigen(LeukocyteAntigen),CellSurfaceAntigenMAX.3,Hly9-Beta,SLAMF5,LeucocyteDifferentiationAntigenCD84,LeukocyteAntigenCD84,SLAMFamilyMember5,CD84Antigen,HCD84,MCD84,LY9B,SLAMfamilymember5,CellsurfaceantigenMAX.3,Hly9-beta,LeukocytedifferentiationantigenCD84,Signalinglymphocyticactivationmolecule5.
Introduction
CD84belongstothesignalinglymphocyteactivationmolecule(SLAM)familywhichformsasubsetofthegreaterCD2cell-surfacereceptorIgsuperfamily.CD84,amembraneglycoprotein,isahomophilicadhesionmoleculefoundinvariousimmunecellstypesandtakespartinregulatingreceptor-mediatedsignalinginthosecells.
Description
CD84HumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining213aminoacids(22-225a.a.)andhavingamolecularmassof23.8kDa(MolecularsizeonSDS-PAGEwillappearatapproximately28-40kDa).
CD84isexpressedwitha6aminoacidsHistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
CD84proteinsolution(0.5mg/ml)containsPhosphateBufferedSaline(pH7.4)and10%glycerol.
StABIlity
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.
Purity
Greaterthan95%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADPKDSEIFTVNGILGESVTFPVNIQEPRQVKIIAWTSKTSVAYVTPGDSETAPVVTVTHRNYYERIHALGPNYNLVISDLRMEDAGDYKADINTQADPYTTTKRYNLQIYRRLGKPKITQSLMASVNSTCNVTLTCSVEKEEKNVTYNWSPLGEEGNVLQIFQTPEDQELTYTCTAQNP
VSNNSDSISARQLCADIAMGFRTHHTGHHHHHH.