Cataloguenumber
PRO-2404
Synonyms
CD79bMolecule,CD79BAntigen(Immunoglobulin-AssociatedBeta),CD79bMolecule,Immunoglobulin-AssociatedBeta,Immunoglobulin-AssociatedB29Protein,B-Cell-SpecificGlycoproteinB29,Ig-Beta,IGB,B29,B-CellAntigenReceptorComplex-AssociatedProteinBetaChain,CD79bAntigen,CD79B,AGM6.
Introduction
CD79Bisa36kDatransmembraneglycoproteinbelongingtotheimmunoglobulinsuperfamily.HeterodimersofCD79AandCD79BconnectwithamembraneattachedimmunoglobulinontheBcellsurfacetocreatetheBcellantigenreceptorcomplex(BCR).CD79AandCD79BareessentialforBCR-mediatedsignalingandsubsequentlyforthedevelopmentandactivationofBlineagecells.
Description
CD79BHumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining140aminoacids(29-159a.a.)andhavingamolecularmassof16.3kDa(MolecularsizeonSDS-PAGEwillappearatapproximately18-28kDa).
CD79Bisexpressedwitha9aminoacidHistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
CD79Bproteinsolution(0.5mg/ml)containsPhosphateBufferedSaline(pH7.4)and10%glycerol.
StABIlity
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADPARSEDRYRNPKGSACSRIWQSPRFIARKRGFTVKMHCYMNSASGNVSWLWKQEMDENPQQLKLEKGRMEESQNESLATLTIQGIRFEDNGIYFCQQKCNNTSEVYQGCGTELRVMGFSTLAQLKQRNTLKDHHHHHH.