Cataloguenumber
PRO-2420
Synonyms
T-cellantigenCD7,GP40,LEU-9,Tp40,TP41,CD7,T-cellleukemiaantigen,T-cellsurfaceantigenLeu-9.
Introduction
T-cellantigenCD7(CD7)isatypeItransmembraneglycoproteinwhichisexpressedonpluripotentialhemapoieticcells,nearlyallhumanthymocytesandsomeperipheralbloodTcells.TheCD7moleculeismissinginasubsetofhumanTcellsundersomephysiologicconditions.AnincreaseinCD7negativeTcellscanbeobservedinanumberofinflammatoryskindiseases.
Description
CD7HumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining164aminoacids(26-180a.a.)andhavingamolecularmassof17.5kDa(MolecularsizeonSDS-PAGEwillappearatapproximately18-28kDa).CD7isexpressedwitha6aminoacidsHistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
CD7proteinsolution(1mg/ml)containsPhosphateBufferedSaline(pH7.4)and10%glycerol.
StABIlity
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.
Purity
Greaterthan95.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADLAQEVQQSPHCTTVPVGASVNITCSTSGGLRGIYLRQLGPQPQDIIYYEDGVVPTTDRRFRGRIDFSGSQDNLTITMHRLQLSDTGTYTCQAITEVNVYGSGTLVLVTEEQSQGWHRCSDAPPRASALPAPPTGSALPDPQTASALPDPPAASALPHHHHHH.