Cataloguenumber
PRO-2445
Synonyms
CD96Molecule,TCell-ActivatedIncreasedLateExpressionProtein,CellSurfaceAntigenCD96,CD96Antigen,TCellActivation,IncreasedLateExpression,T-CellSurfaceProteinTactile,TACTILE.
Introduction
CD96isatypeImembraneproteinwhichisapartoftheimmunoglobulinsuperfamily.CD96functionsascellMarkersinimmune-phynotypingandparticipatesinantigenpresentation.CD96playsaroleintheadhesiveinteractionsofactivatedTandNKcellsthroughthelatephaseoftheimmuneresponse.
Description
CD96HumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining490aminoacids(22-503a.a.)andhavingamolecularmassof54.6kDa(MolecularsizeonSDS-PAGEwillappearatapproximately70-100kDa).
CD96isexpressedwitha8aminoacidsHistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
CD96proteinsolution(0.5mg/ml)containsPhosphateBufferedSaline(pH7.4)and10%glycerol.
StABIlity
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
VWEKTVNTEENVYATLGSDVNLTCQTQTVGFFVQMQWSKVTNKIDLIAVYHPQYGFYCAYGRPCESLVTFTETPENGSKWTLHLRNMSCSVSGRYECMLVLYPEGIQTKIYNLLIQTHVTADEWNSNHTIEIEINQTLEIPCFQNSSSKISSEFTYAWSVEDNGTQETLISQNHLISNSTLLKDRVKLGTDYRLHLSPVQIFDDGRKFSCHIRVGPNKILRSSTTVKVFAKPEIPVIVENNSTDVLVERRFTCLLKNVFPKANITWFIDGSFLHDEKEGIYITNEERKGKDGFLELKSVLTRVHSNKPAQSDNLTIWCMALSPVPGNKVWNISSEKITFLLGSEISSTDPPLSVTESTLDTQPSPASSVSPARYPATSSVTLVDVSALRPNTTPQPSNSSMTTRGFNYPWTSSGTDTKKSVSRIPSETYSSSPSGAGSTLHDNVFTSTARAFSEVPTTANGSTKTNHVHITGIVVNKPKDGMLEHHHHHH.