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Prospec/KLRD1 Antibody/Mouse Anti Human Killer Cell Lectin Like Receptor D1/5µg/ANT-717-5µg

Cataloguenumber
ANT-717
Synonyms
KillerCellLectinLikeReceptorD1,KillerCellLectin-LikeReceptorSubfamilyD,Member1,NKCellReceptor,CD94Antigen,CD94,KP43,KillerCellLectin-LikeReceptorSubfamilyDMember1,NaturalKillerCellsAntigenCD94,KLRD1.
Type
Introduction
KLRD1,alsoknownasKillerCellLectinLikeReceptorD1,isexpressedonthesurfaceofnaturalkillercellsintheinnateimmunesystem.KLRD1functionsasareceptorfortherecognitionofMHCclassIHLA-EmoleculesbyNKcellsandsomecytotoxicT-cells.KLRD1cancreatedisulfide-bondedheterodimerwithNKG2familymembers.CD94&NKG2complexinteractswith(HLA)-E,HumanLeukocyteAntigenontargetcellsonthesurfaceofnaturalkillercells.
Clone
PAT13E3AT.
PhysicalAppearance
Immunogen
Anti-humanKLRD1mAb,isderivedfromhybridizationofmouseF0myelomacellswithspleencellsfromBALB/cmiceimmunizedwitharecombinanthumanKLRD1protein32-279aminoacidspurifiedfromE.coli.
IgSubclass
MouseIgG1heavychainandklightchain.
PurificationMethod
KLRD1antibodywaspurifiedfrommouseasciticfluidsbyprotein-Aaffinitychromatography.
Formulation
1mg/mlcontainingPBS,pH-7.4,10%Glyceroland0.02%SodiumAzide.
StorageProcedures
StABIlity/ShelfLife
Applications
KLRD1antibodyhasbeentestedbyELISAandWesternblotanalysistoassurespecificityandreactivity.Sinceapplicationvaries,however,eachinvestigationshouldbetitratedbythereagenttoobtainoptimalresults.
SafetyDataSheet
SDS