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Prospec/HK1/2/3 Antibody/Hexokinase-1/2/3, Mouse Anti Human/20µg/ANT-726-20µg

Cataloguenumber
ANT-726
Synonyms
Hexokinase-3,EC2.7.1.1,HexokinasetypeIII,HKIII,HXK3,HK3.
Type
Introduction
Hexokinasesphosphorylateglucosetoproduceglucose-6-phosphate,thuscommittingglucosetotheglycolyticpathway.HK3encodeshexokinase3.Similartohexokinases1and2,thisallostericenzymeisinhibitedbyitsproductglucose-6-phosphate.Hexokinase3lacksthehydrophobicN-terminalsequencecriticalfortargetingtomitochondria.Hexpkinase3mayhaveanabolicfunctions,providingH6Pforglycogenorlipidsynthesis.
Clone
PAT4C12AT.
PhysicalAppearance
Immunogen
Anti-humanHK1/2/3mAb,isderivedfromhybridizationofmouseF0myelomacellswithspleencellsfromBALB/cmiceimmunizedwithrecombinanthumanHK1/2/3aminoacids1-923purifiedfromE.coli.
IgSubclass
MouseIgG1heavychainandκlightchain.
PurificationMethod
HK1/2/3antibodywaspurifiedfrommouseasciticfluidsbyprotein-Aaffinitychromatography.
Formulation
1mg/mlcontainingPBS,pH-7.4,10%Glyceroland0.02%SodiumAzide.
StorageProcedures
StABIlity/ShelfLife
Applications
HK1/2/3antibodyhasbeentestedbyELISAandWesternblotanalysistoassurespecificityandreactivity.Sinceapplicationvaries,however,eachinvestigationshouldbetitratedbythereagenttoobtainoptimalresults.
SafetyDataSheet
SDS