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Prospec/CSK Antibody/C-Src Tyrosine Kinase, Mouse Anti Human/5µg/ANT-693-5µg

Cataloguenumber
ANT-693
Synonyms
Tyrosine-proteinkinaseCSK,C-Srckinase,Protein-tyrosinekinaseCYL,CSK,C-SrcTyrosineKinase.
Type
Introduction
C-SrcTyrosineKinase,alsoknownasCSK,regulatescellgrowth,migration,differentiation,andimmuneresponse.CSKPhosphorylatestyrosineresidueslocatedintheC-terminaltailsofSrc-familykinases.CSKisaproteincodinggenewhichsuppressessignalingbyseveralsurfacereceptors.AmongCSK"srelatedpathwaysarePI-3KcascadeandSignalingbyFGFR.
Clone
PAT7C6AT.
PhysicalAppearance
Immunogen
Anti-humanCSKmAb,isderivedfromhybridizationofmouseF0myelomacellswithspleencellsfromBALB/cmiceimmunizedwithrecombinanthumanCSKaminoacids1-450purifiedfromE.coli.
IgSubclass
MouseIgG2bheavychainandκlightchain.
PurificationMethod
CSKantibodywaspurifiedfrommouseasciticfluidsbyprotein-Aaffinitychromatography.
Formulation
1mg/mlcontainingPBS,pH-7.4,10%Glyceroland0.02%SodiumAzide.
StorageProcedures
StABIlity/ShelfLife
Applications
CSKantibodyhasbeentestedbyELISA,WesternblotanalysisandICC/IFtoassurespecificityandreactivity.Sinceapplicationvaries,however,eachinvestigationshouldbetitratedbythereagenttoobtainoptimalresults.
SafetyDataSheet
SDS