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Prospec/SERPINA5 Human/Serpin Peptidase Inhibitor Clade A Member 5 Human Recombinant/10µg/PRO-749-10µg

Cataloguenumber
PRO-749
Synonyms
PAI3,PCI,PROCI,PLANH3,Protein-CInhibitor,SerpinA5,Plasminogenactivatorinhibitor3,PAI-3,SERPINA5.
Introduction
SERPINA5upregulatesTAFIactivationbyinhibitingtheproteinCactivation.SERPINA5isasignificantregulatorintheequilibriumbetweencoagulationandfibrinolysisbydifferentiallyinhibitingtheactivationofTAFIandofProtein-C.SERPINA5belongstotheserpinserineproteinaseinhibitorfamily.SERPINA5proteininhibitsplasminogenactivatorsaswellasactivatedproteinC.SERPINA5issecretedinplasma&liver.SERPINA5isinvolvedincellinflammation,proliferation,apoptosis,tumourcellmigration,invasion,andmetastasis.Moreover,SERPINA5controlstheinvasivepotentialofrenalcellcarcinomabyinhibitingurinaryplasminogenactivatorsecretedbythecells.SERPINA5participtesinregulatingkeyserineproteaseswhichareinvolvedinmetastaticprostatedisease.
Description
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SafetyDataSheet
SDS