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Prospec/PSG1 Human, Sf9/Pregnancy Specific Beta-1-Glycoprotein 1 Human Recombinant, Sf9/2µg/PRO-2452-2µg
Cataloguenumber
PRO-2452
Synonyms
PregnancySpecificBeta-1-Glycoprotein1,PSBG1,B1G1,FetalLiverNon-SpecificCross-ReactiveAntigen1/2,Pregnancy-SpecificBeta-1GlycoproteinC/D,CD66Antigen-LikeFamilyMemberF,PS-Beta-C/D,PS-Beta-G-1,FL-NCA-1/2,PSBG-1,PSGGA,PSG95,SP1,Pregnancy-SpecificBeta-1-Glycoprotein1,Pregnancy-SpecificB-1Glycoprotein,Pregnancy-SpecificGlycoprotein1,CD66fAntigen,DHFRP2,PSGIIA,CD66f,PBG1,PSG1.
Introduction
PregnancySpecificBeta-1-Glycoprotein1(PSG1)isamemberofasubgroupoftranscriptionfactorswhicharephosphorylateduponbindingtopromotersequences.PSGsbelongtothecarcinoembryonicantigen(CEA)familyandfunctionasearlybiochemicalMarkersofsyncytiotrophoblastformation.FurThermore,PSG1isassumedtomediateplacentalvascularmorphogenesisbyenhancingVEGF-Aproductionandendothelialtubeformation.PSG1isamajorproductofthesyncytiotrophoblast,reachingconcentrationsof100-290mg/lattermintheserumofpregnantwomen.
Description
PSG1HumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining394aminoacids(35-419a.a.)andhavingamolecularmassof44.6kDa(MolecularsizeonSDS-PAGEwillappearatapproximately40-57kDa).PSG1isexpressedwitha6aminoacidsHistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
PSG1proteinsolution(0.25mg/ml)containsPhosphateBufferedSaline(pH7.4)and20%glycerol.
StABIlity
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Avoidmultiplefreeze-thawcycles.
Purity
Greaterthan90%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADLQVTIEAEPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSGKWIPHHHHHH.
SafetyDataSheet
SDS
