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Other_recombinant_protein >
Prospec/METRNL Human/Meteorin-Like Protein Human Recombinant/2µg/PRO-2583-2µg

Cataloguenumber
PRO-2583
Synonyms
Meteorin-likeprotein,Subfatin,METRNL.
Introduction
METRNLorMeteorin-likeproteinisahormone,releasedafterphysicalactivity(inskeletalmuscle)orexposuretocold(inADIposetissue),thatinducesenergyrate.METRNLstimulatesenergyratecorrelatewithwhitefatbrowningandraiseglucosetolerance.TheproteinstimulatesdifferenttypesofimmunecellstoenterthefattissueandstarttheirproThermogenicactions.
Description
METRNLHumanRecombinantproducedinE.Coliisasingle,non-glycosylated,polypeptidechain(a.a46-311)containing276aminoacidsincludinga10a.aN-terminalHistag.Thetotalmolecularmassis31.2kDa(calculated).
Source
PhysicalAppearance
Formulation
METRNLfiltered(0.4µm)andlyophilizedfrom0.5mg/mlin50mMacetatebuffer,5%trehalose(w/v)and1mMDTT,pH4.
Solubility
Itisrecommendedtoadd0.1Macetatebuffer,pH4toprepareaworkingstocksolutionofapproximately0.5mg/mlandletthelyophilizedpelletdissolvecompletely.
StABIlity
Purity
Greaterthan95.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
MKHHHHHHASQYSSDRCSWKGSGLTHEAHRKEVEQVYLRCAAGAVEWMYPTGALIVNLRPNTFSPARHLTVCIRSFTDSSGANIYLEKTGELRLLVPDGDGRPGRVQCFGLEQGGLFVEATPQQDIGRRTTGFQYELVRRHRASDLHELSAPCRPCSDTEVLLAVCTSDFAVRGSIQQVTHEPERQDSAIHLRVSRLYRQKSRVFEPVPEGDGHWQGRVRTLLECGVRPGHGDFLFTGHMHFGEARLGCAPRFKDFQRMYRDAQERGLNPCEVGTD.
SafetyDataSheet
SDS
Usage
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theymaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.