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Prospec/LUM Mouse/Lumican Mouse Recombinant/2µg/PRO-2609-2µg

Cataloguenumber
PRO-2609
Synonyms
Lum,Ldc,SLRR2D,Lumican,Keratansulfateproteoglycanlumican,KSPGlumican.
Introduction
LumicanalsoknownasLUMisapartofthesmallleucine-richproteoglycan(SLRP)familywhichcomprisesdecorin,biglycan,fibromodulin,keratocan,epiphycan,andosteoglycin.FurThermore,wecanseethatinthesebifunctionalmolecules,theproteinmoietybindscollagenfibrilsandthehighlychargedhydrophilicglycosaminoglycansregulateinterfibrillarspacings.LumicanisthemainkeratansulfateproteoglycanofthecorneahoweverLUMisalsodistributedininterstitialcollagenousmatricesthroughoutthebody.Lumicanregulatescollagenfibrilorganizationandcircumferentialgrowth,cornealtransparency,epithelialcellmigrationandtissuerepair.
Description
LUMMouseRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining328aminoacids(19-338a.a)andhavingamolecularmassof37.5kDa(Migratesat40-57kDaonSDS-PAGEunderreducingconditions).LUMisfusedtoan8aminoacidHis-tagatC-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
LUMproteinsolution(0.5mg/ml)containingPhosphateBufferedSaline(pH7.4)and20%glycerol.
StABIlity
Purity
Aminoacidsequence
QYYDYDIPLFMYGQISPNCAPECNCPHSYPTAMYCDDLKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDLLENSKIKGKVFSKLKQLKKLHINYNNLTESVGPLPKSLQDLQLTNNKISKLGSFDGLVNLTFIYLQHNQLKEDAVSASLKGLKSLEYLDLSFNQMSKLPAGLPTSLLTLYLDNNKISNIPDEYFKRFTGLQYLRLSHNELADSGVPGNSFNISSLLELDLSYNKLKSIPTVNENLENYYLEVNELEKFDVKSFCKILGPLSYSKIKHLRLDGNPLTQSSLPPDMYECLRVANEITVNVEHHHHHH.
SafetyDataSheet
SDS