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Prospec/FGL1 Human/Fibrinogen Like 1 Human Recombinant/10µg/PRO-2580-10µg

Cataloguenumber
PRO-2580
Synonyms
Fibrinogen-likeprotein1,HP-041,Hepassocin,Hepatocyte-derivedfibrinogen-relatedprotein1,HFREP-1,Liverfibrinogen-relatedprotein1,LFIRE-1,FGL1,HFREP1.
Introduction
FGL1belongstothefibrinogenfamily.FibrinogenLike1ishomologoustothecarboxyterminusofthefibrinogenbeta-andgamma-subunitswhichcomprisesthe4conservedcysteinesoffibrinogensandfibrinogenrelatedproteins.FGL1lackstheplatelet-bindingsite,cross-linkingregionandathrombin-sensitivesitewhicharenecessaryforfibrinclotformation.Fibrinogentakespartinthedevelopmentofhepatocellularcarcinomas.
Description
FGL1HumanRecombinantproducedinE.Coliisasingle,non-glycosylated,polypeptidechain(a.a23-312)containing300aminoacidsincludinga10a.aN-terminalHistag.Thetotalmolecularmassis35.3kDa(calculated).
Source
PhysicalAppearance
Formulation
FGL1filtered(0.4µm)andlyophilizedfrom0.5mg/mlinin100mMcarbonatebuffer,pH9.2.
Solubility
Itisrecommendedtoadddeionizedwatertoprepareaworkingstocksolutionofapproximately0.5mg/mlandletthelyophilizedpelletdissolvecompletely.FGL1isnotsterile!Pleasefiltertheproductbyanappropriatesterilefilterbeforeusingitinthecellculture.
StABIlity
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
MKHHHHHHASLEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKGDENTVIDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMSDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI.
SafetyDataSheet
SDS
Usage
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theymaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.