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Prospec/DCAF7 Human/DDB1 and CUL4 Associated Factor 7 Human Recombinant/5µg/PRO-909-5µg
Cataloguenumber
PRO-909
Synonyms
DDB1-andCUL4-associatedfactor7,WDrepeat-containingprotein68,WDrepeat-containingproteinAn11homolog,DCAF7,HAN11,WDR68,AN11,SWAN-1.
Introduction
DDB1-andCUL4-associatedfactor(DCAF7)isinvolvedincraniofacialdevelopment.TheDCAF7proteinactsupstreamoftheEDN1pathwayandisessentialforformationoftheupperjawequivalent,thepalatoquadrate.TheactivitynecessaryfortheEDN1pathwayfunctionvariesbetweenthefirstandsecondarches.DCAF7associateswithDIAPH1andcontrolsGLI1transcriptionalactivity.DCAF7maybeinvolvedinnormalanddiseasedskindevelopment.
Description
DCAF7HumanRecombinantproducedinE.Coliisasingle,non-glycosylatedpolypeptidechaincontaining298aminoacids(19-295a.a)andhavingamolecularmassof33.6kDa.DCAF7isfusedtoa21aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
DCAF7proteinsolution(1mg/ml)containing20mMTris-HClbuffer(pH8.0),0.4Mureaand1mMDTT.
StABIlity
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Avoidmultiplefreeze-thawcycles.
Purity
Aminoacidsequence
MGSSHHHHHHSSGLVPRGSHMVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFICRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWD.
SafetyDataSheet
SDS