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Prospec/AMH Human/Anti-Mullerian Hormone Human Recombinant/10µg/PRO-2479-10µg

Cataloguenumber
PRO-2479
Synonyms
Anti-Muellerianhormone,AMH,Muellerian-inhibitingsubstance,MIS,MIF.
Introduction
Anti-MullerianHormonealsoknownasAMHisamemberoftheTGF-betafamily.AMHisaglycoproteinwhichisproducedbytheSertolicellsofthetestis,causesregressionoftheMuellerianduct.AMHinhibitsthegrowthoftumorsderivedfromtissuesofMuellerianductorigin.Moreover,AMHparticipatesinLeydigcelldifferentiationandfunctioninadditiontofolliculardevelopmentinadultfemales.
Description
AMHHumanRecombinantproducedinE.coliisasingle,non-glycosylatedpolypeptidechain(a.a452-560)containing118aminoacidsincludinga9a.aN-terminalHistag.Thetotalmolecularmassis12.8kDa(calculated).
Source
EscherichiaColi.
PhysicalAppearance
Formulation
AMHfiltered(0.4µm)andlyophilizedin1mMHCland5%(w/v)trehalose.
Solubility
Itisrecommendedtoadd200µldeionizedwatertoprepareaworkingstocksolutionofapproximately0.5mg/mlandletthelyophilizedpelletdissolvecompletely.AMHisnotsterile!Pleasefiltertheproductbyanappropriatesterilefilterbeforeusingitinthecellculture.
StABIlity
Storelyophilizedproteinat-20°C.Aliquottheproductafterreconstitutiontoavoidrepeatedfreezing/thawingcycles.Reconstitutedproteincanbestoredat4°Cforalimitedperiodoftime;itdoesnotshowanychangeafteroneweekat4°C.
Purity
Greaterthan95.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
MKHHHHHHASAGATAADGPCALRELSVDLRAERSVLIPETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLLISLSEERISAHHVPNMVATECGCR
SafetyDataSheet
SDS
Usage
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theymaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.