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Prospec/Haptoglobin Human, Sf9 /Haptoglobin Human Recombinant, Sf9/2µg/PRO-2586-2µg

Cataloguenumber
PRO-2586
Synonyms
Haptoglobinisoform2,HP,BP,HP2ALPHA2,HPA1S.
Introduction
HaptoglobinorHPisencodedbytheHPgeneinhumans.Haptoglobinbindsfreehemoglobin(whichisreleasedfromerythrocytes)inthebloodplasma,thereforeinhibitstheHboxidativeactivity.ThecomplexthatcontainsHaptoglobinandhemoglobinwillthenbeeliminatedmostlythroughthespleen.
Description
HaptoglobinproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechain(19-347a.a.)andfusedtoa6aaHisTagatC-terminuscontainingatotalof338aminoacidsandhavingamolecularmassof37.7kDa.Haptoglobinshowsmultiplebandsbetween40-57kDaonSDS-PAGE,reducingconditionsandpurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
Haptoglobinproteinsolution(0.25mg/ml)containsPhosphateBufferedSaline(pH7.4)&10%glycerol.
StABIlity
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADLVDSGNDVTDIADDGCPKPPEIAHGYVEHSVRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQVDIGLIKLKQKVSVNERVMPICLPSKDYAEVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYGVYVKVTSIQDWVQKTIAENHHHHHH.
SafetyDataSheet
SDS