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Prospec/EFNB1 Human, Sf9/Ephrin-B1 Human Recombinant, Sf9/10µg/PRO-2543-10µg

Cataloguenumber
PRO-2543
Synonyms
EphrinB1,ELKLigand,Ephrin-B1,Elk-L,EPLG2,LERK2,EFL3,CraniofrontonasalSyndrome(CraniofrontonasalDysplasia),Eph-RelatedReceptorTyrosineKinaseLigand2,EPH-RelatedReceptorTyrosineKinaseLigand2,LERK-2,EFL-3,CFND,EFB1,CFNS,ELKligand,ELK-L,EPH-relatedreceptortyrosinekinaseligand2.
Introduction
EFNB1isamemberoftheEphfamily.Thecell-surfaceproteinsEphrinssplitintotwogroups,ephrin-Aandephrin-B,basedontheirstructureandfunctionandperformasligandsforEphreceptors.ThetransmembraneEFNB1proteinshaveconservedcytoplasmictyrosineresiduesthatarephosphorylateduponinteractionwithanEphBreceptor.Inaddition,EFNB1transducesoutside-insignalsbyC-terminalproteininterfaceswhichinfluenceintegrin-mediatedcellattachmentandmigration.
Description
EFNB1producedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining452aminoacids(28-237a.a.)andhavingamolecularmassof50.3kDa.(MolecularsizeonSDS-PAGEwillappearatapproximately50-70kDa).EFNB1isexpressedwitha242aminoacidhIgG-His-tagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
EFNB1proteinsolution(1mg/ml)contains10%glycerol&PhosphateBufferedSaline(pH7.4).
StABIlity
Purity
Greaterthan90%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQEIRFTIKFQEFSPNYMGLEFKKHHDYYITSTSNGSLEGLENREGGVCRTRTMKIIMKVGQDPNAVTPEQLTTSRPSKEADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDPDGFFNSKLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH.
SafetyDataSheet
SDS