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Prospec/CLEC2B Human, Sf9/C-type Lectin Domain Family 2, Member B Human Recombinant, Sf9/1µg/PRO-2542-1µg

Cataloguenumber
PRO-2542
Synonyms
C-TypeLectinDomainFamily2MemberB,C-Type(CalciumDependent,Carbohydrate-RecognitionDomain)Lectin,SuperfamilyMember2(Activation-Induced),IFN-Alpha-2b-Inducing-RelatedProtein1,C-TypeLectinSuperfamilyMember2,Activation-InducedC-TypeLectin,CLECSF2,IFNRG1,AICL,C-TypeLectinDomainFamily2MemberB,IFN-Alpha2b-InducingRelatedProtein1,HP10085.
Introduction
C-typeLectinDomainFamily2,MemberB(CLEC2B)belongstotheC-typelectin/C-typelectin-likedomain(CTL/CTLD)superfamily.MembersoftheCTL/CTLDfamilyshareacommonproteinfoldandhavevariousfunctions,suchascelladhesion,cell-cellsignaling,glycoproteinturnover,androlesininflammationandimmuneresponse.TheCLEC2BgeneiscloselyconnectedtootherCTL/CTLDsuperfamilymembersonchromosome12p13inthenaturalkillergenecomplexregion.CLEC2Bisexpressedpreferentiallyinlymphoidtissues,andinmosthematopoieticcelltypes.
Description
CLEC2BproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining366aminoacids(26-149a.a.)andhavingamolecularmassof41.7kDa.(MolecularsizeonSDS-PAGEwillappearatapproximately40-57kDa).CLEC2Bisexpressedwitha242aminoacidhIgG-HistagatC-Terminusandpurifiedbyproprietarychromatographictechniques
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
CLEC2Bproteinsolution(0.25mg/ml)containsPhosphateBufferedSaline(pH7.4)and10%glycerol
StABIlity
Purity
Aminoacidsequence
ADPKLTRDSQSLCPYDWIGFQNKCYYFSKEEGDWNSSKYNCSTQHADLTIIDNIEEMNFLRRYKCSSDHWIGLKMAKNRTGQWVDGATFTKSFGMRGSEGCAYLSDDGAATARCYTERKWICRKRIHLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH.
SafetyDataSheet
SDS