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Other_recombinant_protein >
Prospec/CTHRC1 Human, Sf9/Collagen Triple Helix Repeat Containing 1 Human Recombinant, Sf9/2µg/PRO-2606-2µg

Cataloguenumber
PRO-2606
Synonyms
Collagentriplehelixrepeat-containingprotein1isoform1,CTHRC1,ProteinNMTC1.
Introduction
Collagentriplehelixrepeat-containingprotein1orCTHRC1actsasanegativeregulatorofcollagenmatrixdeposition.Theproteinissecretedfroma28kDaproteinwhichisglycosylatedandveryconservedfromlowerchordatestomammals.CTHRC1isfoundqualitativelyinplasmaofhealthyhumansubjects.CTHRC1plasmalevelsarealsosignificantlyelevatedduringpregnancy,indiabetes,ininflammatoryandinfectiousconditions,insubjectswithacutemyeloidleukemiabutnotinsubjectswithsolidcancers.CTHRC1ishighlyconnectedwithcalcifiedtissuesandcartilaginousmatrix,butnotwithendothelialcells.
Description
CTHRC1producedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining222aminoacids(31-243a.a.)andhavingamolecularmassof24.1kDa(MolecularsizeonSDS-PAGEwillappearatapproximately28-40kDa).CTHRC1isexpressedwitha6aminoacidHistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
CTHRC1proteinsolution(0.5mg/ml)containsPhosphateBufferedSaline(pH7.4)and10%glycerol.
StABIlity
Purity
Aminoacidsequence
ADPSEIPKGKQKAQLRQREVVDLYNGMCLQGPAGVPGRDGSPGANGIPGTPGIPGRDGFKGEKGECLRESFEESWTPNYKQCSWSSLNYGIDLGKIAECTFTKMRSNSALRVLFSGSLRLKCRNACCQRWYFTFNGAECSGPLPIEAIIYLDQGSPEMNSTINIHRTSSVEGLCEGIGAGLVDVAIWVGTCSDYPKGDASTGWNSVSRIIIEELPKHHHHHH.
SafetyDataSheet
SDS