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Prospec/S100A6 Human/S100 Calcium Binding Protein A6 Human Recombinant/20µg/PRO-148-20µg

Cataloguenumber
PRO-148
Synonyms
Introduction
S100A6isamemberoftheS100familyofproteinscontaining2EF-handcalcium-bindingmotifs.S100proteinsarelocalizedeitherinthecytoplasmorthenucleusofawiderangeofcells.S100proteinsareinvolvedintheregulationofanumberofcellularprocessessuchascellcycleprogressionanddifferentiation.Thereareatleast13membersintheS100genefamily,whicharelocatedasaclusteronchromosome1q21.S100A6functioninstimulationofprolactinsecretionandexocytosis.ChromosomalrearrangementsandalteredexpressionoftheS100A6geneareimplicatedinmelanoma.
Description
S100A6HumanRecombinantfusedwitha20aminoacidHistagatN-terminusproducedinE.Coliisasingle,non-glycosylated,polypeptidechaincontaining110aminoacids(1-90a.a.)andhavingamolecularmassof12.3kDa.TheS100A6ispurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
StABIlity
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Avoidmultiplefreeze-thawcycles.
Purity
Aminoacidsequence
MGSSHHHHHHSSGLVPRGSHMACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDLDRNKDQEVNFQEYVTFLGALALIYNEALKG.
SafetyDataSheet
SDS