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Prospec/TGFBR1 Human/Transforming Growth Factor Beta Receptor I Human Recombinant/2µg/PKA-111-2µg
Cataloguenumber
PKA-111
Synonyms
TGFBR1,AAT5,ACVRLK4,ALK-5,ALK5,ESS1,LDS1,LDS1A,LDS2A,MSSE,SKR4,tbetaR-I,TGFR-1.
Introduction
TGFBR1isasingle-passtype1membraneproteinwhichisapartoftheTGFBreceptorsubfamilyandtheproteinkinasesuperfamily.TGFBR1isasecretedproteinthatperformsmanycellularfunctionssuchasthecontrolofcellgrowth,celldifferentiation,cellproliferationandapoptosis.TGFBR1alsocontrolstheimmunesystemandshowsdifferentactivitiesonvarioustypesofcell,orcellsatdifferentdevelopmentalstages.
Description
TGFBR1producedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining342aminoacids(27-126a.a.)andhavingamolecularmassof38.0kDa.(MolecularsizeonSDS-PAGEwillappearatapproximately40-57kDa).TGFBR1isexpressedwitha242aminoacidhIgG-HistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
TGFBR1proteinsolution(0.5mg/ml)PhosphateBufferedSaline(pH7.4)containing10%glycerol.
Aminoacidsequence
ADLLLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTETTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTVKSSPGLGPVELVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH.
StABIlity
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
SafetyDataSheet
SDS

