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Prospec/PPP3R2 Human/Protein Phosphatase 3 Regulatory subunit, Beta Isozyme Human Recombinant/5µg/ENZ-103-5µg
Cataloguenumber
ENZ-103
Synonyms
CalcineurinsubunitBtype2,CalcineurinB-likeprotein,CBLP,CalcineurinBII,CNBII,PPP3R1-like,Proteinphosphatase2Bregulatorysubunit2,Proteinphosphatase3regulatorysubunitBbetaisoform,PPP3R2,PPP3RL.
Introduction
PPP3R2isacalcium-dependent,calmodulinstimulatedserine/threonineproteinphosphatase.Ineukaryotes,thephosphorylationanddephosphorylationofproteinsonserineandthreonineresiduesisacrucialmeansofregulatingawiderangeofcellularfunctionsincludingdivision,homeostasisandapoptosis.Ordinarilytheproteinphosphatase(PP)holoenzymeisatrimericcomplexcomposedofaregulatorysubunit,avariablesubunitandacatalyticsubunit.
Description
PPP3R2HumanRecombinantfusedwitha20a.a.HistagatN-terminusproducedinE.Coliisasingle,non-glycosylated,polypeptidechain(a.a.1-173)containing193aminoacidsandhavingamolecularmassof22kDa.ThePPP3R2ispurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
ThePPP3R2solution(0.5mg/ml)contains20mMTris-HClbuffer(pH8.0),10%glyceroland1mMDTT.
StABIlity
Purity
Aminoacidsequence
MGSSHHHHHHSSGLVPRGSHMSTMGNEASYPAEMCSHFDNDEIKRLGRRFKKLDLDKSGSLSVEEFMSLPELRHNPLVRRVIDVFDTDGDGEVDFKEFILGTSQFSVKGDEEQKLRFAFSIYDMDKDGYISNGELFQVLKMMVGNNLTDWQLQQLVDKTIIILDKDGDGKISFEEFSAVVRDLEIHKKLVLIV.
SafetyDataSheet
SDS

