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Prospec/CD72 Human, Sf9/CD72 Human Recombinant, Sf9/2µg/PRO-2608-2µg
Cataloguenumber
PRO-2608
Synonyms
CD72,CD72b,LYB2,B-celldifferentiationantigenCD72,Lyb-2.
Introduction
CD72antigenisamemberofthetypeIIintegralmembraneglycoproteinswhichincludesotherrelatedcellsurfacemoleculaessuchastheasialoglycoproteinreceptors,CD23andtheKupffercellrecpeotr.TheexposureofBcellstoCD72antibodiesactivatesavarietyofsignallingpathwaysandcaninduceMHCclassIIexpressionandBcellproliferation.CD72antigenisexpressedonallcellsofBcelllineagewiththeexceptionofplasmacellsandweaklyonhumantissuemacrophages.
Description
CD72HumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining485aminoacids(117-359a.a.)andhavingamolecularmassof55.3kDa(MolecularsizeonSDS-PAGEwillappearatapproximately50-70kDa).CD72isexpressedwitha242aminoacidhIgG-HistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
CD72proteinsolution(0.5mg/ml)contains50mMTris-HClbuffer(pH6.8),0.2MNaCl,2mMDTTand50%glycerol.
StABIlity
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Avoidmultiplefreeze-thawcycles.
Purity
Greaterthan90%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADPRYLQVSQQLQQTNRVLEVTNSSLRQQLRLKITQLGQSAEDLQGSRRELAQSQEALQVEQRAHQAAEGQLQACQADRQKTKETLQSEEQQRRALEQKLSNMENRLKPFFTCGSADTCCPSGWIMHQKSCFYISLTSKNWQESQKQCETLSSKLATFSEIYPQSHSYYFLNSLLPNGGSGNSYWTGLSSNKDWKLTDDTQRTRTYAQSSKCNKVHKTWSWWTLESESCRSSLPYICEMTAFRFPDLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH.
SafetyDataSheet
SDS
