Cataloguenumber
PRO-2618
Synonyms
B3GAT1,CD57,GLCATP,GLCUATP,HNK1,LEU7,NK-1,NK1,Beta-1,3-glucuronyltransferase1,GlucuronosyltransferaseP,GlcAT-P,UDP-GlcUA:glycoproteinbeta-1,3-glucuronyltransferase,GlcUAT-P.
Introduction
CD57alsocalledB3GAT1ispartoftheglucuronyltransferasegenefamily.CD57exhibitsstrictacceptorspecificity,recognizingnonreducingterminalsugarsandtheiranomericlinkages.CD57takespartintheglucuronyltransferreactionduringthebiosynthesisofthecarbohydrateepitopeHNK-1.
Description
CD57HumanRecombinantproducedinBaculovirusisasingle,glycosylated,polypeptidechaincontaining549aminoacids(28-334aa)andhavingamolecularmassof62.3kDa.CD57isfusedtoa242aminoacidhIgG-His-TagatC-terminusandpurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
TheCD57solution(0.25mg/ml)contains20mMTris-HClbuffer(pH7.5),10%glyceroland0.1MNaCl.
StABIlity
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADPTLAPLLAVHKDEGSDPRRETPPGADPREYCTSDRDIVEVVRTEYVYTRPPPWSDTLPTIHVVTPTYSRPVQKAELTRMANTLLHVPNLHWLVVEDAPRRTPLTARLLRDTGLNYTHLHVETPRNYKLRGDARDPRIPRGTMQRNLALRWLRETFPRNSSQPGVVYFADDDNTYSLELFEEMRSTRRVSVWPVAFVGGLRYEAPRVNGAGKVVGWKTVFDPHRPFAIDMAGFAVNLRLILQRSQAYFKLRGVKGGYQESSLLRELVTLNDLEPKAANCTKILVWHTRTEKPVLVNEGKKGFTDPSVEILEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH.
SafetyDataSheet
SDS
Usage
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.