Cataloguenumber
PRO-2514
Synonyms
CD55Antigen,DAF,CD55Molecule,CHAPLE,CromerBloodGroupAntigen,ComplementDecay-AcceleratingFactor,CROM.
Introduction
Decay-AcceleratingFactorIsoform1orCD55,isaproteinthatattachedtothecellmembranethroughglycophosphatidylinositol(GPI)anchor.CD55regulatesthecomplementsystemintheoutermembrane.Theproteinisareceptortomanytypesofenterovirusessuchascoxsackieviruses.CD55iswidelyscatteredamidsthematopoietic&non-hematopoieticcells.TheCD55hasacrucialpartintumOrigenesis,autocrineloopsforcellrescueandevasionofapoptosis,cellmotility,invasivenessetc.
Description
CD55producedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechain(35-353a.a.)andfusedtoa9aaHisTagatC-terminuscontainingatotalof328aminoacidsandhavingamolecularmassof36kDa.CD55showsmultiplebandsbetween40-57kDaonSDS-PAGE,reducingconditionsandpurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
StABIlity
Purity
Aminoacidsequence
ADPDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSHHHHHH.
SafetyDataSheet
SDS