Cataloguenumber
PRO-2533
Synonyms
Plateletglycoprotein4isoform1,BDPLT10,CHDS7,FAT,GP3B,GP4,GPIV,PASIV,SCARB3,GlycoproteinIIIb,GPIIIB,LeukocytedifferentiationantigenCD36,PAS-4,Plateletcollagenreceptor,PlateletglycoproteinIV,Thrombospondinreceptor.
Introduction
CD36isanintegralmembraneproteinfoundinavarietycelltypesofmammals,itispartoftheclassBscavengerreceptorfamily.InhumansitisencodedbytheCD36gene.Theproteinbindstoligandssuchasnativelipoproteins,collagen,long-chainfattyacids,thrombospondinetc.CD36playsacrucialroleintransportingfattyacidsintothecell.
Description
CD36producedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining652aminoacids(30-439a.a.)andhavingamolecularmassof73.9kDa.(MolecularsizeonSDS-PAGEwillappearatapproximately70-100kDa).CD36isexpressedwitha242aminoacidhIgG-HistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
CD36proteinsolution(0.5mg/ml)containsphosphatebufferedsaline(pH7.4)and10%glycerol.
StABIlity
Purity
Greaterthan85.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADLGDLLIQKTIKKQVVLEEGTIAFKNWVKTGTEVYRQFWIFDVQNPQEVMMNSSNIQVKQRGPYTYRVRFLAKENVTQDAEDNTVSFLQPNGAIFEPSLSVGTEADNFTVLNLAVAAASHIYQNQFVQMILNSLINKSKSSMFQVRTLRELLWGYRDPFLSLVPYPVTTTVGLFYPYNNTADGVYKVFNGKDNISKVAIIDTYKGKRNLSYWESHCDMINGTDAASFPPFVEKSQVLQFFSSDICRSIYAVFESDVNLKGIPVYRFVLPSKAFASPVENPDNYCFCTEKIISKNCTSYGVLDISKCKEGRPVYISLPHFLYASPDVSEPIDGLNPNEEEHRTYLDIEPITGFTLQFAKRLQVNLLVKPSEKIQVLKNLKRNYIVPILWLNETGTIGDEKANMFRSQVTGKINLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH.
SafetyDataSheet
SDS