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Prospec/Fractalkine Human, Sf9/Fractalkine (CX3CL1) Human Recombinant, Sf9/10µg/CHM-042-10µg
Cataloguenumber
CHM-042
Synonyms
Fractalkine,CX3CL1,Neurotactin,CX3Cmembrane-anchoredchemokine,SmallinducIBLecytokineD1,NTN,NTT,CXC3,CXC3C,SCYD1,ABCD-3,C3Xkine.
Introduction
Fractalkinesolubleformischemotacticfort-cellsandmonocytes,butnotforneutrophils.Fractalkinemembrane-boundformpromotesadhesionofthoseleukocytestoendothelialcells.FractalkineregulatesleukocyteadhesionandmigrationprocessesattheendotheliumandbindstoCX3CR1.Fractalkinegeneislocatedonhumanchromosome16alongwithsomeCCchemokinesknownasCCL17andCCL22.
Description
FractalkineHumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining323aminoacids(25-339aa)andhavingamolecularmassof34.3kDa.Fractalkineisfusedtoa8aminoacidHistagatC-terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
TheFractalkinesolution(1mg/ml)contains10%GlycerolandPhosphateBufferedSaline(pH7.4).
StABIlity
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
QHHGVTKCNITCSKMTSKIPVALLIHYQQNQASCGKRAIILETRQHRLFCADPKEQWVKDAMQHLDRQAAALTRNGGTFEKQIGEVKPRTTPAAGGMDESVVLEPEATGESSSLEPTPSSQEAQRALGTSPELPTGVTGSSGTRLPPTPKAQDGGPVGTELFRVPPVSTAATWQSSAPHQPGPSLWAEAKTSEAPSTQDPSTQASTASSPAPEENAPSEGQRVWGQGQSPRPENSLEREEMGPVPAHTDAFQDWGPGSMAHVSVVPVSSEGTPSREPVASGSWTPKAEEPIHATMDPQRLGVLITPVPDAQAATRLEHHHHHH
SafetyDataSheet
SDS