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Prospec/FGF 18 Human/Fibroblast Growth Factor-18 Human Recombinant/25µg/CYT-120-25µg
Cataloguenumber
CYT-120
Synonyms
Introduction
Fibroblastgrowthfactor18(FGF18)isamemberofthelargeFGFfamilywhichhasatleast23members.FGF18isabindinggrowthfactorwithacore120aminoacidFGFdomainwhichallowsforacommontertiarystructure.FGFsareexpressedinthecourseoftheembryonicdevelopmentandinrestrictedadulttissues.FGF-18isanindispensableregulatoroflongboneandcalvarialdevelopment.FGF-18signalsviaFGFR1c,2c,3c,and4.
Description
FGF-18HumanRecombinantproducedinE.coliisasingle,non-glycosylatedpolypeptidechaincontaining181aminoacidsandhavingamolecularmassof21.1kDa.TheFGF-18ispurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
Solubility
ItisrecommendedtoreconstitutethelyophilizedFGF-18insterile18MΩ-cmH2Onotlessthan100µg/ml,whichcanthenbefurtherdilutedtootheraqueoussolutions.
StABIlity
Purity
Aminoacidsequence
AEENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQPELQKPFKYTTVTKRSRRIRPTHPA.
BIOLOGicalActivity
SafetyDataSheet
SDS