
Cataloguenumber
CYT-1101
Synonyms
RELT,TNFReceptor,ReceptorExpressedInLymphoidTissues,TumorNecrosisFactorReceptorSuperfamilyMember19L,RELTTumorNecrosisFactorReceptor,TNFRSF19L,TumorNecrosisFactorReceptorSuperfamily,Member19-Like,TRLT.
Introduction
RELTisexpressedinhematopoietictissuesandperipheralbloodleukocytesandisapartofthetumornecrosisfactorreceptorsuperfamily.RELTmediatesactivationofNF-kappa-BandtakespartinT-cellactivation.overexpressionofRELTinHEK-293cellsinducesp38andJNKsignallingandleadstoapoptosis.itcanalsocostimulateT-cellproliferationinthepresenceofCD3signalling.
Description
RELTproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining376aminoacids(26-162a.a.)andhavingamolecularmassof41.4kDa.(MolecularsizeonSDS-PAGEwillappearatapproximately40-57kDa).RELTisexpressedwitha239aminoacidhIgG-His-tagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
RELTproteinsolution(0.5mg/ml)contains10%glycerol&PhosphateBufferedSaline(pH7.4).
StABIlity
Purity
Aminoacidsequence
STTLWQCPPGEEPDLDPGQGTLCRPCPPGTFSAAWGSSPCQPHARCSLWRRLEAQVGMATRDTLCGDCWPGWFGPWGVPRVPCQPCSWAPLGTHGCDEWGRRARRGVEVAAGASSGGETRQPGNGTRAGGPEETAAQVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
SafetyDataSheet
SDS