
Cataloguenumber
CYT-1024
Synonyms
CD213A2,CT19,IL-13R,IL13BP,IL-13receptorsubunitalpha-2,IL-13Rsubunitalpha-2,CD_antigen=CD213a2,Interleukin-13-bindingprotein.
Introduction
Interleukin13Receptor,Alpha2(IL13RA2)isamemberofthetypeIcytokinereceptorfamily,Type5subfamily.IL13RA2isrelatedtol13RA1,asubunitoftheinterleukin13receptorcomplex.IL13RA2bindsIL13withhighaffinity,thoughlackingthecytoplasmicdomain,anddoesnotappeartofunctionasasignalmediator.IL13RA2playsaroleintheinternalizationofIL13.
Description
IL13RA2HumanRecombinantproducedinSf9Insectcellsisasingle,glycosylatedpolypeptidechaincontaining559aminoacids(27-343a.a.)andhavingamolecularmassof64.3kDa(MolecularsizeonSDS-PAGEwillappearatapproximately70-100kDa).IL13RA2isexpressedwitha239aminoacidhIgG-HistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
IL13RA2proteinsolution(0.5mg/ml)containsPhosphatebufferedsaline(pH7.4)and10%glycerol.
StABIlity
Purity
Greaterthan85.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADLDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
SafetyDataSheet
SDS