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Prospec/TIMP2 Human, Sf9/Tissue Inhibitor of Metalloprotease 2 Human Recombinant, Sf9/1µg/ENZ-936-1µg-1µg
Prospec/TIMP2 Human, Sf9/Tissue Inhibitor of Metalloprotease 2 Human Recombinant, Sf9/1µg/ENZ-936-1µg-1µg
商品编号:
ENZ-936-1µg-1µg
品牌:
prospecbio
市场价:
¥1000.00
美元价:
450.00
产品分类:
其它酶
公司分类:
Other_enzymes
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Catalogue number
ENZ-936
Synonyms
TIMPMetallopeptidase Inhibitor 2, Tissue Inhibitor Of Metalloproteinases 2, CSC-21K,Tissue Inhibitor Of Metalloproteinase 2, TIMP-2, DDC8, Metalloproteinaseinhibitor 2.
Introduction
TIMP2 belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases that take part in degradation of the extracellular matrix. Besides having an inhibitory role against metalloproteinases, the encoded protein has a exclusive part among TIMP family members in its capability to directly suppress the proliferation of endothelial cells. Consequently, the encoded protein is crucial to the conservation of tissue homeostasis by suppressing the production of quiescent tissues as an answer to angiogenic factors, and by inhibiting protease activity in tissues undergoing renovation of the extracellular matrix.
Description
TIMP2 produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 200 amino acids (27-220a.a.) andhaving a molecular mass of 22.5kDa.
(Molecular size on SDS-PAGE will appear atapproximately 18-28kDa).
TIMP2 is expressed with a 6amino acid His tag at C-Terminus and purified by proprietary chromatographictechniques.
Source
Sf9,Baculovirus cells.
Physical Appearance
Sterile Filtered clear solution.
Formulation
TIMP2 protein solution (0.25mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrierprotein (0.1% HSA or BSA).
Avoid multiple freeze-thawcycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
CSCSPVHPQQ AFCNADVVIR AKAVSEKEVD SGNDIYGNPI KRIQYEIKQIKMFKGPEKDI EFIYTAPSSA VCGVSLDVGG KKEYLIAGKA EGDGKMHITL CDFIVPWDTL STTQKKSLNHRYQMGCECKI TRCPMIPCYI SSPDECLWMD WVTEKNINGH QAKFFACIKR SDGSCAWYRGAAPPKQEFLD IEDPHHHHHH.
Safety Data Sheet
SDS
Usage
Prospec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作,1947年出生于以色列。1991-1997创建ReProGen 公司,从事细胞因子和趋化因子的大量生产及纯化;1997-2000创建ProSpec-TechnoGene,主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。
ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.
Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....
Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.
ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.
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