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Prospec/MMP 8 Human/Matrix Metalloproteinase-8 Human Recombinant/2.5U/ENZ-301-2.5U-2.5U
Catalogue number
ENZ-301
Synonyms
EC 3.4.24.34, Matrix metalloproteinase-8, MMP-8, PMNL-CL, HNC, CLG1.
Introduction
Full-length recombinant human neutrophil MMP-8, latent form.Matrix metalloproteinase 8 (MMP-8), degrades interstitial collagens, acting preferentially on collagen type I. Increased full-length MMP-8 protein was associated with infiltration into the skin of neutrophils, which are the major cell type that expresses MMP-8.MMP-8 is synthesized and stored in specific granules in neutrophil leukocytes. MMP-8 activity is therefore regulated by factors such as surface-bound ligands (IgG or complement components) that release it through degranulation.Once released and activated through proteolytic or oxidative mechanisms, MMP-8 plays a major role in the connective tissue turnover that accompanies inflammatory processes.
Description
Source
Physical Appearance
Formulation
Stability
Purity
Biological Activity
Applications
Used as a standard for analyzing mammalian colagenase activity.
Safety Data Sheet
SDS