4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
prospecbio(授权代理)
主营:主营:重组和天然蛋白、细胞因子和生长因子、趋化因子、蛋白激酶、激素和酶、热休克蛋白、病毒抗原、单克隆及多克隆抗体。
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > monoclonal_antibody > Prospec/MHC I类,H-2K抗体,FITC/MHC I类,(H-2K)小鼠抗体,FITC/500µg/ANT-267-500µg-500µg
商品详细Prospec/MHC I类,H-2K抗体,FITC/MHC I类,(H-2K)小鼠抗体,FITC/500µg/ANT-267-500µg-500µg
Prospec/MHC I类,H-2K抗体,FITC/MHC I类,(H-2K)小鼠抗体,FITC/500µg/ANT-267-500µg-500µg
Prospec/MHC I类,H-2K抗体,FITC/MHC I类,(H-2K)小鼠抗体,FITC/500µg/ANT-267-500µg-500µg
商品编号: ANT-267-500µg-500µg
品牌: prospecbio
市场价: ¥5000.00
美元价: 2250.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Catalogue number

ANT-267

Type

Mouse Antibody Monoclonal.

Introduction

MHC Class I is a membrane spanning molecule consisting of 2 proteins. MHC Class I is just about 350 amino acids in length, with roughly 75 amino acids at the carboxylic end comprising the transmembrane and cytoplasmic portions. The remaining 270 amino acids, are divided into three globular domains labeled Alpha-1, Alpha-2 and Alpha-3 prime, with Alpha-1 being closest to the amino terminus and Alpha-3 closest to the membrane. The second portion of the molecule is a small globular protein called Beta-2 Microglobulin. It links primarily with the Alpha-3 prime domain and is essential for MHC stability. The MHC ability to show a vast range of antigenic peptides for T cell recognition needs a compromise between broad specificity and high affinity. Both MHC class I and MHC class II show an exceptional structure while the peptide main chain is tightly bound and peptide side chains show less restrictive interactions. It is primarily the peptide side-chain contacts and conformational variability that ensures that the peptide-MHC complex presents an antigenically unique surface to T cell receptors.

Clone

NYRmH-2K.

Immunogen

Purified mouse LN cells (C57Bl/6 anti-BALB/c) .

Ig Subclass

Mouse IgG2b.

Specificity

Recognizes most mouse H-2K haplotypes (k,p,q,r,s). Does NOT react with H-2kd.

Purification Method

Ion exchange column.

Formulation

1mg/ml in PBS (after reconstitution).

Storage Procedures

Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

Solubility

Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Applications

Cytotoxic and staining antibody. For staining, use 10ml/1,000,000 cells. Titer for cytotoxicity should be determined by the investigator.

Available Conjugates

This antibody is also available as unconjugated antibody and conjugated to Biotin.

Safety Data Sheet

SDS

Usage

ProSpec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
    ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作,1947年出生于以色列。1991-1997创建ReProGen 公司,从事细胞因子和趋化因子的大量生产及纯化;1997-2000创建ProSpec-TechnoGene,主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。       ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.       Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....       Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.       ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.