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Prospec/MCM7 PAT1G8AT Antibody/Minichromosome Maintenance Complex Component 7, Clone PAT1G8AT, Mouse Anti Human/20µg/ANT-719-20µg-20µg

Cataloguenumber
ANT-719
Synonyms
MinichromosomeMaintenanceComplexComponent7,MCM7MinichromosomeMaintenanceDeficient7(S.Cerevisiae),MinichromosomeMaintenanceDeficient(S.Cerevisiae)7,DNAReplicationLicensingFactorMCM7,HomologofS.CerevisiaeCdc47,CDC47Homolog,P1CDC47,PNAS146,P85MCM,MCM2,CDC47,P1.1-MCM3,EC3.6.4.12.
Type
Introduction
MCM7isahighlyconservedmini-chromosomemaintenanceprotein(MCM)vitalforeukaryoticgenomereplicationinitiation.TheMCMproteinsformahexamericproteincomplexwhichisakeycomponentofthepre-replicationcomplex(pre_RC)whichtakespartinreplicationforksformationandinDNAreplicationrelatedproteinsrecruitment.TheMCMcomplexiscomprisedofMCM2,4,6and7proteinsandpossessesDNAhelicaseactivity,suchasDNAunwinding.
Clone
PAT1G8AT.
Immunogen
Anti-humanMCM7mAb,isderivedfromhybridizationofmouseF0myelomacellswithspleencellsfromBALB/cmiceimmunizedwitharecombinanthumanMCM7protein1-414aminoacidspurifiedfromE.coli.
IgSubclass
MouseIgG2bheavychainandklightchain.
PurificationMethod
MCM7antibodywaspurifiedfrommouseasciticfluidsbyprotein-Gaffinitychromatography.
Formulation
1mg/mlcontainingPBS,pH-7.4,&0.1%SodiumAzide.
StorageProcedures
StABIlity/ShelfLife
Applications
MCM7antibodyhasbeentestedbyELISAandWesternblotanalysistoassurespecificityandreactivity.Sinceapplicationvaries,however,eachinvestigationshouldbetitratedbythereagenttoobtainoptimalresults.
SafetyDataSheet
SDS