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Prospec/FABP3 Antibody/Mouse Anti Human Fatty Acid Binding Protein-3/5µg/ANT-698-5µg-5µg
Cataloguenumber
ANT-698
Synonyms
Fattyacid-bindingproteinheart,H-FABP,Heart-typefattyacid-bindingprotein,Musclefattyacid-bindingprotein,M-FABP,Mammary-derivedgrowthinhibitor,MDGI,FABP3,FABP11,O-FABP.
Type
Introduction
RecombinantFattyAcidBindingProteinisanewlyintroducedplasmaMarkerofacutemyocardialinfarction(AMI).TheplasmakineticsofFABP(15kD)closelyresemblethoseofmyoglobininthatelevatedplasmaconcentrationsarefoundwithin2hoursafterAMIandreturntonormalgenerallywithin18to24hours.ButtheconcentrationofFABPintheskeletalmuscleis20timeslowerthanincardiactissue(formyoglobinthesamecontentforcardiacandskeletaltissue),thatmakesFABPtobemorecardiacspecificthanmyoglobin.ThismakesFABPausefulbiochemicalmarkerfortheearlyassessmentorexclusionofAMI.FABPalsoappearstobeausefulplasmamarkerfortheestimationofmyocardialinfarctsize.
Clone
PAT9F10AT.
PhysicalAppearance
Immunogen
Anti-humanFABP3mAb,isderivedfromhybridizationofmouseF0myelomacellswithspleencellsfromBALB/cmiceimmunizedwitharecombinanthumanFABP3protein1-133aminoacidspurifiedfromE.coli.
IgSubclass
MouseIgG1heavychainandklightchain.
PurificationMethod
FABP3antibodywaspurifiedfrommouseasciticfluidsbyprotein-Aaffinitychromatography.
Formulation
1mg/mlcontainingPBS,pH-7.4,10%Glyceroland0.02%SodiumAzide.
StorageProcedures
StABIlity/ShelfLife
Applications
FABP3antibodyhasbeentestedbyELISAandWesternblotanalysistoassurespecificityandreactivity.Sinceapplicationvaries,however,eachinvestigationshouldbetitratedbythereagenttoobtainoptimalresults.
SafetyDataSheet
SDS