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Prospec/DKK3 Antibody/Mouse Anti Human Dickkopf-Related Protein 3/20µg/ANT-707-20µg-20µg

Cataloguenumber
ANT-707
Synonyms
Dickkopf3homolog(Xenopuslaevis),dickkopf-relatedprotein3,regulatedinglioma,RIG,RIG-like7-1,RIG-like5-6,Dkk-3,REIC.
Type
Introduction
Dickkopf-relatedprotein3(DKK3)belongstotheDKKproteinfamilyincludingDkk-1,2,3and-4.DKK3isa350aminoacidsecretedglycoproteinwhichiscomprisedofanN-terminalsignalpeptideand2conservedcysteine-richdomainsthatareseparatedbya12aminoacidlinkerregion.DKK3isinvolvedinembryonicdevelopmentthroughitsinhibitionoftheWNTsignalingpathway.DKK3geneexpressionisdecreasedinavarietyofcancercelllinesanditmayactasatumorsuppressorgene.
Clone
PAT103B5AT.
PhysicalAppearance
Immunogen
Anti-humanDKK3mAb,isderivedfromhybridizationofmouseF0myelomacellswithspleencellsfromBALB/cmiceimmunizedwitharecombinanthumanDKK3protein(22-350aminoacidspurifiedfromE.coli.
IgSubclass
MouseIgG1heavychainandklightchain.
PurificationMethod
DKK3antibodywaspurifiedfrommouseasciticfluidsbyprotein-Aaffinitychromatography.
Formulation
1mg/mlcontainingPBS,pH-7.4,10%Glyceroland0.02%SodiumAzide.
StorageProcedures
StABIlity/ShelfLife
Applications
DKK3antibodyhasbeentestedbyELISAandWesternblotanalysistoassurespecificityandreactivity.Sinceapplicationvaries,however,eachinvestigationshouldbetitratedbythereagenttoobtainoptimalresults.
SafetyDataSheet
SDS