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Prospec/IMPA1 Antibody/Inositol Monophosphatase 1, Mouse Anti Human/100µg/ANT-625-100µg-100µg

Prospec/IMPA1 Antibody/Inositol Monophosphatase 1, Mouse Anti Human/100µg/ANT-625-100µg-100µg
商品编号:
ANT-625-100µg-100µg
品牌:
prospecbio
市场价:
¥9000.00
美元价:
3825.00
产品分类:
抗人
公司分类:
Anti_Human
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Catalogue number
ANT-625
Synonyms
Inositol monophosphatase 1, IMP 1, IMPase 1,Inositol-1(or 4)-monophosphatase 1, Lithium-sensitive myo-inositolmonophosphatase A1, IMPA1, IMPA, IMP.
Type
Mouse Anti Human Monoclonal.
Introduction
Inositol monophosphatase1 (IMPA1) is responsible for the provision of inositol essential for synthesis of phosphatidylinositol and polyphosphoinositides. IMPA1 has a central role in the phosphatidylinositol signaling pathway by catalyzing the hydrolysis of inositol monophosphates. IMPA1 has been recognized as the pharmacological target for lithium action in the brain. The IMPA1 enzyme has a magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and ensuing depletion of inositol for phosphatidylinositol synthesis may perhaps explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder.
Clone
PAT2G5AT.
Physical Appearance
Sterile filtered colorless solution.
Immunogen
Anti-human IMPA1 mAb, isderived from hybridization of mouse F0 myeloma cells with spleen cells fromBALB/c mice immunized with a recombinant human IMPA1protein 1-277amino acids purified fromE. coli.
Ig Subclass
Mouse IgG1 heavy chain and k light chain.
Purification Method
IMPA1 antibody was purified from mouse ascitic fluids byprotein-A affinity chromatography.
Formulation
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Storage Procedures
For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C.
Prevent freeze thaw cycles.
Stability / Shelf Life
12 months at -20°C. 1 month at 4°C.
Applications
The antibody has been tested by ELISA, Westernblot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity.Since application varies, however, each investigation should be titrated by thereagent to obtain optimal results.
Safety Data Sheet
SDS
Usage
ProSpec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作,1947年出生于以色列。1991-1997创建ReProGen 公司,从事细胞因子和趋化因子的大量生产及纯化;1997-2000创建ProSpec-TechnoGene,主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。
ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.
Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....
Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.
ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.
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