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Prospec/IDS Antibody/Iduronate 2-Sulfatase, Mouse Anti Human/20µg/ANT-745-20µg-20µg

Cataloguenumber
ANT-745
Synonyms
Iduronate2-Sulfatase,Alpha-L-IduronateSulfateSulfatase,Idursulfase,SIDS,Iduronate2-Sulfatase14KDaChain,Iduronate2-Sulfatase42KDaChain,HunterSyndrome,EC3.1.6.13,MPS2,Iduronate2-sulfatase,Alpha-L-iduronatesulfatesulfatase,Idursulfase.
Type
Introduction
Iduronate2-SulfatasealsoknownasIDS,belongstothehighly-conservedsulfatasefamilyofenzymeswhichcatalyzethehydrolysisofO-sulfateandN-salfateestersfromavarietyofsubstrates.IDSisessentialforthelysosomaldegradationoftheglycosaminoglycans(GAG)heparansulfateaswellasdermatansulfate.FurThermore,IDShydrolyzesthe2-sulfategroupoftheIDSunitsoftheGAG.
Clone
PAT6H4AT.
PhysicalAppearance
Immunogen
Anti-humanIDSmAb,isderivedfromhybridizationofmouseF0myelomacellswithspleencellsfromBALB/cmiceimmunizedwitharecombinanthumanIDSprotein26-550aminoacidspurifiedfromE.coli.
IgSubclass
MouseIgG2bheavychainandklightchain.
PurificationMethod
IDSantibodywaspurifiedfrommouseasciticfluidsbyprotein-Aaffinitychromatography.
Formulation
1mg/mlcontainingPBS,pH-7.4,10%Glyceroland0.02%SodiumAzide.
StorageProcedures
StABIlity/ShelfLife
Applications
TheantibodyhasbeentestedbyELISA,Westernblotanalysis,FlowcytometryandICC/IFtoassurespecificityandreactivity.Sinceapplicationvaries,however,eachinvestigationshouldbetitratedbythereagenttoobtainoptimalresults.
SafetyDataSheet
SDS