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Prospec/HDAC2 Antibody/Histone Deacetylase 2, Mouse Anti Human/5µg/ANT-742-5µg-5µg
Cataloguenumber
ANT-742
Synonyms
Histonedeacetylase2,YAF1,HD2,YY1-associatedfactor1,transcriptionalregulatorhomologRPD3,RPD3,EC3.5.1.98.
Type
Introduction
HDAC2isamemberofthehistonedeacetylasefamilythatperformsthroughtheconstructionoflargemultiproteincomplexesandareinchargeofthedeacetylationoflysineresiduesontheN-terminalregionofthecorehistones.HDAC2formstranscriptionalrepressorcomplexesbyrelatingtoadiversityofproteins,likeYY1-amammalianzinc-fingertranscriptionfactor.Inaddition,HDAC2hasavitalpartintranscriptionalregulation,cellcycleprogressionanddevelopmentalprocedures.
Clone
PAT3B1AT.
PhysicalAppearance
Immunogen
Anti-humanHDAC2mAb,isderivedfromhybridizationofmouseF0myelomacellswithspleencellsfromBALB/cmiceimmunizedwithrecombinanthumanHDAC2aminoacids1-488purifiedfromE.coli.
IgSubclass
MouseIgG2bheavychainandκlightchain.
PurificationMethod
HDAC2antibodywaspurifiedfrommouseasciticfluidsbyprotein-Aaffinitychromatography.
Formulation
1mg/mlcontainingPBS,pH-7.4,10%Glyceroland0.02%SodiumAzide.
StorageProcedures
StABIlity/ShelfLife
Applications
HDAC2antibodyhasbeentestedbyELISA,Westernblotanalysis,ICC/IFandFlowcytometrytoassurespecificityandreactivity.Sinceapplicationvaries,however,eachinvestigationshouldbetitratedbythereagenttoobtainoptimalresults.
SafetyDataSheet
SDS