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Prospec/HSA Protein/HSA Human Protein/500mg/PRO-354-500mg-500mg
Cataloguenumber
PRO-354
Synonyms
HSA,ALB,PRO0883,PRO0903,PRO1341,DKFZp779N1935,GIG20,GIG42,PRO1708,PRO2044,PRO2619,PRO2675,UNQ696,SA,HSA.
Introduction
HSAissynthesizedintheliveraspreproalbuminwhichhasanN-terminalpeptidethatisremovedbeforethenascentproteinisreleasedfromtheroughendoplasmicreticulum.Theproduct,proalbumin,isinturncleavedintheGolgivesiclestoproducethesecretedHSA.HSAisasoluble,monomericproteinwhichcomprisesaboutone-halfofthebloodserumprotein.HSAfunctionsprimarilyasacarrierproteinforsteroids,fattyacids,andthyroidhormonesandplaysaroleinstABIlizingextracellularfluidvolume.Mutationsinthisgeneonchromosome4resultinvariousanomalousproteins.HSAisaglobularunglycosylatedserumproteinofmolecularweight65,000.ThehumanHSAgeneis16,961nucleotideslongfromtheputative"cap"sitetothefirstpoly(A)additionsite.Itissplitinto15exonswhicharesymmetricallyplacedwithinthe3domainsthatarethoughttohavearisenbytriplicationofasingleprimordialdomain.HSAiswidelyusedtostabilizebloodvolumegenerallyfromdonorsbutthefearofcontaminationsuchasHIV&Hepatitishasenticedgreatinterestintherecombinantformwhichisidenticaltothenaturalblood.Suitableforuseinbiochemical,excipient(aninertsubstanceusedasadiluentorvehicleforadrug),culturemediaandchromatographicapplications.
Description
HSAcontains584aminoacidresiduesderivedfromtheprototypicalHSAsequence.
Source
PhysicalAppearance
Formulation
Stability
HSAalthoughstableatroomtemperaturefor2weeksshouldbestoredat4°C.
Purity
SafetyDataSheet
SDS