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Prospec/SNX3 Human/Sorting Nexin 3 Human Recombinant/1mg/PRO-246-1mg-1mg
Cataloguenumber
PRO-246
Synonyms
Sortingnexin-3,ProteinSDP3,SNX3,SDP3,Grd19,MCOPS8.
Introduction
Sortingnexin3(SNX3)belongstothelargefamilyofhydrophilicproteins,whichinteractwithvariousreceptortypesandareinvolvedinintracellulartrafficking.SNX3interactswithphosphatidylinositol-3-phosphate,andisinvolvedinproteintrafficking.SNX3comprisesadistinctsubgroupofnexins,whichsharelesssequencesimilarityoutsideofthePXdomainandhavesignificantlydifferentbindingaffinitiesforthetyrosinekinasereceptors.
Description
SNX3producedinE.Coliisasingle,non-glycosylatedpolypeptidechaincontaining182aminoacids(1-162a.a)andhavingamolecularmassof20.9kDa.SNX3isfusedtoa20aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
SNX3proteinsolution(1mg/ml)containing20mMTris-HClbuffer(pH8.0),1mMDTT,20%glyceroland0.1MNaCl.
StABIlity
SNX3HumanRecombinantalthoughstableat4°Cfor1week,shouldbestoredbelow-18°C.Pleasepreventfreezethawcycles.
Purity
Aminoacidsequence
MGSSHHHHHHSSGLVPRGSHMAETVADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIRHA.
SafetyDataSheet
SDS